
In this episode, host John Fredericks and Dr. Peter McCullough discuss the growing market for anti‑inflammatory drugs and introduce the Wellness Company’s peptide‑based “Regenerate” drops, which aim to repair musculoskeletal tissue rather than merely mask pain. They also cover natural testosterone‑boosting supplements (Mars) and oral GLP‑1‑based appetite suppressors as alternatives to injectable weight‑loss drugs, emphasizing a holistic, non‑prescription approach to vitality for older adults. Throughout, John shares his personal health transformation—losing 40 lb, improving lab markers, and maintaining a rigorous fitness routine—thanks to these products, while Dr. McCullough provides scientific context on peptides and the $130 billion anti‑inflammatory industry.

In this episode, Unity Stokes talks with Kim Fisher, Chief Impact Officer of Startup Health’s Food is Medicine Moonshot and Program Director of UC Davis’s Innovation Institute for Food and Health, about the rapid emergence of the food‑as‑medicine movement. Fisher...
The episode examines the pervasive diet‑tribalism that claims any single eating plan is a flawless solution, arguing instead that all diets are trade‑off‑driven optimizations against the typical American diet, which is high in excess calories, refined carbs, and ultra‑processed foods....

In this episode of Longevity by Design, Dr. Andrea Mayer discusses the scientific evidence behind multivitamin and mineral supplements, highlighting that they may modestly improve cognition, mood, and blood pressure in at-risk or nutritionally deficient individuals, but show little benefit...

In this episode, host Molly Eastman talks with Dr. Matt Bernstein, a psychiatrist and CEO of Accord, about metabolic psychiatry and how diet—particularly ketogenic nutrition—affects mental health, anxiety, and sleep. Dr. Bernstein explains the science behind ketosis, its impact on...

In this episode, Dr. Paola Sebastiani explains how the genetics of extreme longevity are far more complex than a single "longevity gene," highlighting the growing list of genetic variants—such as APOE, chromosome 9 loci, and inflammation‑related regions on chromosome 6—that...

In this episode of Iron Culture, hosts Eric Trexler and Dr. Eric Helms dissect a class‑action lawsuit alleging that David protein bars dramatically under‑report calories and fat due to the use of a novel fat replacer (EPC). They explain how...
In this AMA episode, Dr. Peter Atiyah tackles a wide array of practical health questions, covering how health priorities shift across the decades, the hierarchy of chronic disease risk, and the most useful consumer health metrics. He discusses the role...

In this AMA sneak‑peek, Dr. Peter Atiyah fielded listener questions on practical longevity strategies, covering how health priorities shift across the 20s, 40s, and 60s+, the hierarchy of chronic disease risk (cardiovascular, cancer, neurodegeneration, metabolic), and the most useful consumer...
In this episode Chris Kresser reviews a new American Journal of Clinical Nutrition study of over 5,000 Chinese adults aged 80+, which found vegetarians and especially vegans were 19‑29% less likely to become centenarians than omnivores, with the effect driven...

Chris Masterjohn, a nutritional scientist and mitochondrial biologist, launched Mitome, a consumer‑focused platform for mitochondrial health testing. In a conversation with Razib Khan, he critiqued the COVID‑19 response, alleging authorities overstated certainty and faced attempts at censorship. Masterjohn also argued...

In this episode the host explores the emerging link between chronic fatigue—including Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)—and gut health, emphasizing how gut dysbiosis may drive persistent exhaustion. They explain the gut microbiome as a complex ecosystem, using a garden metaphor...